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Nuclei isolation from the anatomical preparation was quality controlled by FACS sorting (see Supplementary material online, Figure S8 ) prior to measurements

Study participants will be randomly assigned to receive either a placebo, liver medication NNC0194-0499, semaglutide, cagrilintide (an amylin-analog), or a combination
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Genetic factors affecting your peptide metabolismlike GLP1R rs6923761 variantscan influence how well you tolerate semaglutide and whether a lower consistent dose works better than sporadic higher doses
