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If gallbladder disease is diagnosed, management depends on severity and may range from conservative observation for asymptomatic gallstones to cholecystectomy (surgical gallbladder removal) for acute cholecystitis or symptomatic cholelithiasis

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Readers are encouraged to check ClinicalTrials.gov and Eli Lilly's official communications for the most current trial status, as this information may change
The GLP-1 receptor activation component of tirzepatide may provide some beta cell protective effects, potentially slowing the autoimmune destruction of remaining beta cells in patients with residual beta cell function
