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In turn, its intended to support weight management

GLP-1 class safety monitoring should include awareness of these important risks: Pancreatitis : Patients should promptly report severe abdominal pain, with or without vomiting Gallbladder disease : Report symptoms of biliary colic or cholecystitis Acute kidney injury : Maintain adequate hydration, especially if experiencing nausea/vomiting Hypoglycemia : Increased risk when used with insulin or sulfonylureas Suicidal ideation : For patients using Wegovy or Zepbound, monitor for mood changes Patients should be counseled to report any neck swelling, difficulty swallowing, persistent hoarseness, or palpable thyroid nodules, as these warrant evaluation regardless of GLP-1 use

When chronic weight management is the main goal, Wegovy or Mounjaro are commonly considered, as both are supported by large-scale trials focused on sustained reduction in body weight

However, slower semaglutide titration (starting at 0.25 mg weekly) is often recommended to allow your body to adapt while on TRT