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doi: 10.1016/j.mcn.2015.10.005 [DOI] [PubMed] [Google Scholar] 155

GLP-3 (Reta) Mechanism of Action Acts as an agonist at three receptors the GIP receptor, the GLP-1 receptor, and the glucagon receptor the defining "triple agonist" pharmacology that separates it from single- and dual-incretin compounds

For weekly retatrutide injections, that gives each site nearly a full month of recovery time
