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Primary outcome was weight loss post at least 3 months of therapy

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The OASIS 4 trial found that patients taking the oral Wegovy pill lost an average of 13.6% of their body weight over 64 weeks, while the STEP 1 trial for injectable Wegovy showed 14.9% weight loss over 68 weeks

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Inagaki N, Seino Y, Takeda J, Yano H, Yamada Y, Bell GI, et al

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The body gradually adapts, and for most people, the severity decreases over time even as the dose increases

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