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The term emerged organically from patient reports and clinical observations, not from a single published study
Lin Q, Xue Y, Zou H, Ruan Z, Ung COL, Hu H (2022) Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials
There is no pharmacological reason you cannot start both simultaneously
The anti-inflammatory and antifibrotic effects of GLP-1 RAs further reinforce their therapeutic potential in NASH
