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How long nausea lasts depends on the medication and dose and is most pronounced when beginning the medication or increasing the dose

It is prescribed as an adjunctive therapy, meant to complement your individualized dietary choices, physical activity regimen, and any other diabetes medications you may be taking

When food stays in your stomach longer and your appetite is reduced, its easier to feel uncomfortably full especially at the beginning of treatment or when your dose increases

Tirzepatide still raises resting heart rate by 2 to 10 bpm at any dose (a GLP-1 class effect), and Bryan Johnsons microdose trial logged a 3 bpm increase along with a sleep-quality drop