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567 Advance of peptide-based vaccines Overview of peptide-based vaccines Since the 18th century, from the eradication of smallpox to the current global COVID-19 pandemic, vaccines have played a critical role in protecting humans and livestock from infectious diseases

An evening routineperhaps alongside brushing teeth or taking other medicationscreates a predictable habit that reduces missed doses

However, advances in whole exome sequencing and bioinformatics have been used to identify individual mutations, predict novel antigens and their peptide ligands, and assess peptide-HLA affinity
