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J.LitwinS.ZileM.et al (2025)

At the same time, some users experience anxiety, low mood, or a flat affect, reporting diminished pleasure from food and social rituals that once revolved around eating and drinking (14)

Some individuals tolerate tirzepatide remarkably well from the start because their genetic makeup predisposes them to efficient dual-receptor signaling

By stimulating both GLP-1 and GIP receptors, it reduces appetite, prolongs feelings of fullness, enhances insulin sensitivity, and could potentially increase your body's calorie-burning rates
