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Description
Tirzepatide 15mg is the most frequently cited high-therapeutic dose in published incretin research, corresponding to the upper protocol strength used in metabolic and dose-response studies
This timeline represents what happens on the starting dose, typically 2.5mg per week

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In brief, in this work, we observed that the lixisenatide and high-dose efpeglenatide, which are both exendin-4 derivatives, were associated with increased events of hearing loss in comparison with the controls