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glp-1 approved for type 1 diabetes Prescriptions Spike Despite Lack of FDA Approval: Study Scripts for GLP-1, SGLT2 Drugs
Description
JACC Basic Transl Sci (2018) 3(6):84457

Within this context, metabolic stability may depend on proportionality between substrate availability and pharmacologically induced metabolic demand

They bind to the same receptors but resist the enzymatic breakdown (by DPP-4) that rapidly degrades natural GLP-1

GLP-1RAs and cardiovascular-renal outcomes in type 2 diabetes systematic review (2021) highlights significant reductions in cardiovascular events, kidney disease progression, and mortality among GLP-1 users
