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More specifically, the ARC nucleus of the hypothalamus has been highlighted as one of the main sites mediating this action as chemical lesion of the ARC in rats ablates the anorectic action of GLP-1 (Tang-Christensen et al., 1998)

Given that there are several subtypes of IBS and that the conditions etiology and symptom profiles vary, this is another limitation of the study

doi: 10.1152/physrev.00034.2006 [DOI] [PubMed] [Google Scholar] 60.Kim W, Egan JM

Neuroprotection of GLP-1/GIP receptor agonist via inhibition of mitochondrial stress by AKT/JNK pathway in a Parkinsons disease model
