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In contrast, another GLP1R agonist , with a shorter half-life of around 13 hours (Liraglutide) achieved only 5.5% reduction in the same time span [22] , demonstrating that improving half-life can result in better outcomes

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Since youre only at 7.5 mg at week 12, theres still significant room to increase

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Mare KU, Sabo KG, Wengoro BF, Lahole BK

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The key word is "steady." A single early or late injection does not meaningfully disrupt steady-state drug levels

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