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The tumor uptake values of our PEGylated probe at 60-min post-injection in the resected organs of mice bearing INS-1 xenografts (Right thigh: 37.3 4.5%ID/g, Inside pancreas: 37.7 4.4%ID/g) showed comparable or higher values than those of other 18 F-labeled non-PEGylated modified exendin-4 probes

Unlike mass production, this allows us to ensure that the peptides we ship are 'fresh' and haven't been sitting on a shelf for extended periods, slowly undergoing degradation

Tirzepatide has two non-coded amino acid residues at positions 2 and 13 (Aib, -aminoisobutyric acid), and is acylated on K20 P (P indicates that the residue belongs to the peptide) with a Glu-2OEG linker and C18 fatty diacid moiety

revealed that the FDA is preparing to loosen restrictions on over a dozen previously banned peptides, potentially moving them from the agencys category 2 list back to category 1