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So from the 1970s when you first began your work as a young would-be surgeon, on ulcers to basically in 1993 and then the early 2000s when the GLP-1s were approved for use in diabetes, several decades have gone by, and then just in the, almost seems like with the flip of a switch, the drugs have changed the lives of tens of millions of people

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Moreover, the evaluation of glycemic homeostasis at the time of its discontinuation clearly showed how its effect is mainly to mask rather than prevent the progression to T2D [44]

Kidney Protection and Diabetic Nephropathy GLP-1 receptor agonists reduce albuminuria, slow eGFR decline, and lower markers of renal inflammation in patients with diabetic kidney disease