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Effects of liraglutide on neurodegeneration, blood flow and cognition in Alzheimers disease - protocol for a controlled, randomized double-blinded trial

Both preclinical and clinical studies suggest that GLP-1 RAs reduce systemic and central inflammation, potentially restoring immune homeostasis in brain regions critical for emotional regulation and reward processing, such as the prefrontal cortex and limbic structures [26,82,84]

Additionally, they found elevated activity in monocyte-related genetic pathways associated with the development of fibrosis in individuals with diabetes

Research consistently shows that a significant portion of lost weight is regained when treatment is stopped
