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89 Rates of non-fatal stroke are reduced in some but not all GLP-1 CVOTs, with meta-analyses demonstrating 16% reduction in risk of stroke across multiple CVOTs in people with T2D

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In a partial hepatectomy-induced behavior study using male Sprague-Dawley rats, surgical trauma induced an exacerbated spatial learning and memory impairment, while exendin-4 treatment suppressed the activation of nuclear factor kappa-B (NF-B) and IL-1, and thus ameliorated hepatectomy-induced behavioral deficits and inflmmation (63)