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Surprisingly, despite the reduction in plasma DPP-4 activity, sitagliptin did not lower plasma TG excursions or apoB48 nor apoB100 levels during a LTT, with or without tyloxapol (Figure 9)

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Until those results are in, the recommendation is extrapolated from non-pharmacologic weight-loss literature plus 2024-2025 case reports of GLP-1 patients who lifted and held their lean mass [11]