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Parallel randomized studies in Hashimoto thyroiditis and Graves disease should pre-specify metabolic co-endpoints (Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) and Magnetic Resonance Imaging-Proton Density Fat Fraction (MRI-PDFF) for liver fat) to test the immunometabolic hypothesis suggested by observational signals and secondary analyses [32,60]

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Glucagon can increase heart rate (a chronotropic effect) and the force of the heart's contractions (an inotropic effect)

Multiple users in gut health subreddits describe seeing a difference within a few days of starting Lemme Debloat, which combines clinically studied probiotics with digestive enzymes
