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Hydralazine IV 510 mg bolus q2030 min (often used in obstetrics)

By activating GLP-1 receptors, tirzepatide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying

Central Alpha-2 Agonists Examples: Clonidine Methyldopa (safe in pregnancy) Side effects: Sedation Rebound hypertension if stopped abruptly 8

Additionally, studies have reported substantial improvements in headache frequency and severity, with 76.9% of patients achieving at least a 50% reduction in monthly headache days when treated with GLP-1 RAs like semaglutide or liraglutide [5, 8]