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The takeaway here is direct

Muscle and Fat (Insulin Sensitivity): GLP-1 RAs enhance glucose uptake in muscle and adipose tissue via the PI3K/Akt pathway, improving overall insulin sensitivity (Zheng et al., 2024)

X., Zhu, X

I gained 60 pounds in 3 weeks (false or extreme outlier) gets more engagement than I experienced gradual weight regain of approximately 2 pounds monthly over 18 months totaling 36 pounds, which represents 72% regain from my 50-pound weight loss, consistent with published discontinuation data (accurate but boring)
