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No human birth defect registry or large prospective pregnancy cohort has yet evaluated GLP-1 exposure, so recommendations remain conservative
What the Research Shows About GLP-1 Medications and Mental Health According to a 2024 systematic review published in the National Library of Medicine, GLP-1 receptor agonists have been associated with several potential mental health benefits across animal and human studies
These include introduction of d-amino acids, ,-dialkylated amino acids like Aib, N-methylated amino acids, -amino acids, amide bond surrogates, 87 PEGylation, 88 glycosylated amino acids, halogenated amino acids, 41,72,73 and conformational restrictions
