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In 2022, a phase 3 randomized, controlled clinical trial demonstrated that tirzepatide led to a 20 percent reduction in body weight over 72 weeks

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Tracking daily steps often reveals substantial activity decreases during plateau periods

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Zepbound (November 2023) for chronic weight management Real-world data : Growing post-market evidence supporting efficacy and safety in diverse populations Cardiovascular outcomes : SURPASS-CVOT trial evaluating cardiovascular endpoints Key Differences Summary# Receptor pharmacology : Retatrutide is a triple agonist (GIP/GLP-1/glucagon)

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Ozempic indicates superior outcomes with a broader metabolic impact

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