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A systematic review comparing these medications found that retatrutide (12 mg) achieved 22% weight loss from baseline, compared to 18% for tirzepatide and 14% for semaglutide

Weeks 1 through 3: The adjustment phase This is when urinary changes are most noticeable

However, doctors prescribe weight loss medications (like GLP-1s) because losing weight is the most effective way to treat the underlying cause

Exploratory analyses found no meaningful differences in effect between participants with baseline BPs above versus below the cohort median baseline BP or between those with controlled versus uncontrolled hypertension