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Laxatives, especially when used frequently, can also lead to significant fluid loss
Nonetheless, pharmacological therapeutic development for MAFLD based on the mechanisms of action, adverse events, and efficacy is reviewed and recommended in clinical practice guidelines (CPGs) issued by the liver international society in the Americas (AASLD), 6 Europe (EASL), 12 and Asia (APASL)

"Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor"

If your diarrhea is persistent and fits that description, ask your provider about testing and options like a bile acid binder
