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Mechanisms of GLP-1RAs actions relevant to the gut In the gastrointestinal system GLP-1RAs delay stomach emptying, increase satiety signals, decrease intestinal motility, and regulate bile acid metabolism [1, 5]

Increased risk of acute pancreatitis and biliary disease observed in patients with diabetes PubMed 19208917

Preclinical evidence is more mixed, with some animal models showing muscle preservation under certain conditions [3], but the clinical human data from high-risk populations is less reassuring

#Semaglutide #GLP1 #PharmaStrategy #IndiaPharma #MetabolicHealth #PharmaMarketing #HealthcareInnovation #ObesityCare To view or add a comment, sign in Ozempic was approved as a diabetes drug in 2017