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Moreover, different subtypes may progress at different rates, with implications for the timing of intervention approaches in a personalized management strategy (Geifman et al., 2018)
Other genetic loci: Polymorphisms in genes such as CNR1, CTRB1/2 andTCF7L2, have shown associations with GLP-1RA response, particularly liraglutide, affecting glycemic control and metabolic parameters [14,133,135]
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