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However, in the Type 1 Diabetes Exchange Clinic Registry, the risk of Level 3 hypoglycaemia was increased not only in those whose HbA 1c was below 7.0% (53 mmol/mol), but also in people with an HbA 1c above 7.5% (58 mmol/mol) [41]

The search strategy combined the Medical Subject Heading (MeSH) terms exenatide OR liraglutide OR semaglutide OR dulaglutide OR albiglutide OR lixizenatide AND diabetes mellitus, type 2 AND a filter to identify RCTs 14

Semaglutide in early type 1 diabetes

When Prednisone Use Makes Semaglutide Less Effective High-dose prednisone (above 20 mg daily) nearly always overwhelms semaglutide's weight loss benefits, regardless of injection strength or formulation