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Furthermore, risks of urinary tract infections, volume depletion, and ketoacidosis have also been reported, highlighting the need for vigilant monitoring of patients on SGLT-2i [8, 9]

Sotagliflozin in patients with diabetes and chronic kidney disease

Notably, dual GIP and GLP-1 receptor agonists produced more potently inhibited AgRP neurons and suppressed food intake than either agonist alone (46)