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Our comprehensive approach includes expert guidance, nutritional counseling, and ongoing support

Method A literature search was performed in PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar during March 2025September 2025, using combinations of the following terms: GLP-1 receptor, GLP-1R agonist, GLP-1 signalling, semaglutide, liraglutide, exenatide, dulaglutide, salivary glands, xerostomia, hyposalivation, oral adverse effects, biased agonism, -arrestin, cAMP, GPCR signaling, albumin binding, pharmacovigilance

The metabolic clearance occurs by proteolytic cleavage of the tirzepatide peptide backbone, -oxidation of the C20 fatty diacid moiety, and by amide hydrolysis

With the nausea, vomiting and pain gone, her appetite returned and she regained weight.