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Description
Patients suffering with chronic pain (pain that persists more than 3 months) have realized the benefit of weight loss, even 10 lbs
In animal models of obesity, baseline serotonin release from the hypothalamus was found to be lower [91]
Semaglutides STEP program showed an average weight loss of roughly 15% over 68 weeks
[Wadden STEP 3, JAMA 2021] STEP 5 Trial (Nature Medicine 2022) Long-term data: patients maintained an average 15.2% weight loss over 2 years of continuous semaglutide use, with sustained metabolic improvements including reduced HbA1c, blood pressure, and waist circumference
