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Long-Term Weight Loss Benefits While Semaglutide delivers impressive short-term results, its true value lies in its long-term benefits

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Some GLP-1 medications are approved for certain adolescents with obesity, but microdosing and weight loss strategies in teens are not standard care

Behavioral intervention involved counseling by a dietitian or equivalent healthcare professional every 4 weeks through in-person visits or telephone sessions, focusing on adhering to a reduced-calorie diet (500 kcal deficit per day compared to estimated energy expenditure at randomization) and increased physical activity (encouraging 150 minutes per week, such as walking), with daily recording (via diary, app, or other tools) reviewed during counseling sessions