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While its full safety profile is still being established in Phase 3 trials, initial data from Phase 2 trials suggest that retatrutide is generally well-tolerated

Dulaglutida (Trulicity): La dosis inicial es de 0.75 mg una vez por semana, que puede aumentarse a 1.5 mg semanalmente
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The paw withdrawal latency (PWL) to heat was measured after either intraperitoneal or oral gavage administration of glucose (2.0 g/kg body weight) in a volume of 200 L or the same volume of vehicle (0.9% saline) ( n = 5 per group)
