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A 2018 case report and literature review found that this supplement may cause liver toxicity, inflammation, and fibrosis

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Understanding the relationship between GLP-1 therapy and bone health helps clinicians and patients make informed treatment decisions while implementing appropriate monitoring and protective strategies for skeletal integrity during therapy

Additionally, novel combination therapiessuch as Tirzepatide, which combines a GLP-1 analogue with glucose-dependent insulinotropic polypeptide (GIP)-are rapidly gaining traction, and it is expected that new formulations will continue to emerge, incorporating peptides capable of modulating metabolism and thermogenesis (Jastreboff et al., 2022
