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Additionally, the cardiac magnetic resonance substudy of the SUMMIT trial revealed that compared with placebo, tirzepatide treatment of obese HFpEF patients reduced the LV mass and paracardial adipose tissue volume, with the changes in the LV mass paralleling the degree of weight loss [166]
The culture supernatant was harvested by centrifugation at 6000 g for 20 min and clarified by filtration
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GLP-1s support weight management by mimicking a hormone naturally produced in the body that regulates appetite
