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Yes, semaglutide and blood pressure medications can be combined safely, but your physician should monitor your blood pressure regularly and may adjust your antihypertensive medication as weight loss reduces your blood pressure naturally

The synergistic effect makes combination therapy attractive for patients requiring stronger glycemic control who haven't achieved targets on monotherapy
We found that prolonged fasting duration was a more important determinant of gastric emptying and aspiration risk than withholding GLP-1 therapy
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