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Description
Tirzepatide, a novel twincretin targeting both GLP-1 and GIP receptors, has demonstrated efficacy for treating T2DM in the SURPASS clinical trial program [168] and overweight/obesity in the SURMOUNT studies [169]
Some laboratory studies suggest that GLP-1 analogues may modulate these neurotransmitter systems, potentially affecting cognitive performance and impulsivity, though these findings remain largely preclinical
Wang W, Mei A, Qian H, Li D, Xu H, Chen J, et al
An enhanced body composition further supports long-term fat loss
