glp 1 fgf21 agonist boehringer GLP-1 receptor agonists and next-generation metabolic hormone therapies in chronic kidney disease Current Insights, Advantages and Challenges
Description
This is important because weight loss itself can reduce inflammation
doi: 10.1038/s41467-020-14309-w 24 IshibashiYMatsuiTTakeuchiMYamagishiS
Specifically, while obesity surgery and LIRA/PYY 3-36 co-administration resulted in comparable changes in body weight in obese rats, only surgery resulted in profound changes to the hypothalamic transcriptome
The New Pharmaceutical Imperative With strong evidence suggesting systemic benefits far beyond glycemic control and weight managementincluding cardiovascular protection and effects on inflammationGLP-1s are now viewed as foundational longevity therapeutics
