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A diverse pipeline of potential therapies for DKD exists, including incretin agonists, endothelin receptor antagonists, aldosterone synthase inhibitors, soluble guanylate cyclase stimulators and agents that target inflammatory pathways such as Janus kinase/Janus kinase 2 inhibitors and IL-6 monoclonal antibodies

(2023) American Society of Anesthesiologists consensusbased guidance on preoperative management of patients (adults and children) on glucagonlike peptide1 receptor agonists, USA

The Physiology of the Interactions Between GLP-1RAs and the BBB Location of GLP-1R and Structure of GLP-1RAs Jensen et al conducted a study in the CNS by isolating and purifying a novel specific monoclonal GLP-1R antibody and detecting the location of GLP-1R using an in situ hybridization technique

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