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While GLP-1 medications can be administered at any time of day (consistent with prescribing information), some patients report personal preference for evening administration

This anxiogenic role of GLP-1 is likely tightly linked with the role brain GLP-1Rs play in interoceptive stress responses (108, 111)

*These statements have not been evaluated by the Food and Drug Administration (FDA)

This new medication may help reduce the effects of GLP-1-based drugs on muscle strength and therefore improve functionality even further compared to someone not on the new medication who is just taking tirzepatide. Writing in the journal Nature Medicine, researchers in the US reported how they randomly divided 102 participants into two groups, with 51 given apitegromab alongside tirzepatide, and the other 51 given a placebo with tirzepatide