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Our previous study on shepherds from the Polish Tatra Mountains based on modified 13C-urea breath testing (UBT) (17) and serology revealed a very high active Hp infection rate and high incidence of cytotoxic CagA seropositivity, as well as increased pro-inflammatory serum cytokine levels compared to control subjects without sheep contact (18)

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Its expression was elevated in -cells of diabetic patients, particularly in immature and senescent subtypes, along with its targets (GSTA4, GSTM3, GCLC, CYP2R1)