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Key Takeaways GLP-1 medication starts showing initial effects and early signs of appetite reduction and improved blood sugar control within the first few weeks

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DISCUSSION We leveraged longitudinal measurements, wearable technology, and causal inference to characterize cardiovascular and behavioral responses during the initial 12 wk of GLP-1 RA therapy

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Beyond 12 hours at room temperature, semaglutide should be considered compromised and discarded

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