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They propose based on rodent and monkey studies that this kind of molecule, when administered at high enough doses, may result in weight loss comparable to the weight loss seen with drugs that include GLP-1 as a target, and without the tolerability issues like nausea and vomiting that often come with the approved treatments, according to a peer-reviewed draft paper published this week

Although constipation may cause back pain in some situations, they are often unrelated and can be symptoms of different health conditions

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It is usually done to make sure your symptoms are not caused by a heart problem rather than a complication of COPD