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[DOI] [PubMed] [Google Scholar] 20.Salvatore T., Nevola R., Pafundi P.C., Monaco L., Ricozzi C., Imbriani S., Rinaldi L., Sasso F.C

Function and regulationincretin axis GLP-1 and its receptor GLP-1 secretion, in response to nutrient intake, leads to the release of insulin through the GLP-1 receptor (GLP-1R) and together with other incretin hormones accounts for 5070% of total post-prandial insulin release [17]

Typical clinical doses range from about 1,000 to 1,500 mg per day divided across meals

These trials are among the largest peptide weight loss studies ever conducted, with thousands of participants across multiple continents and diverse populations