glp 1 agonist function Mechanisms of action of GLP-1RA Understanding GLP-1 receptor agonists and

The main concerns with GLP-1 agonist drugs include: GI side effects (nausea, diarrhea, vomiting, constipation, abdominal pain) High out-of-pocket cost for those who do not quality under insurance Risk of inadequate nutrition (reduced intake + insufficient nutrition counseling) Significant loss of muscle mass & bone density High discontinuation rates (with lost weight regained) Limited public & clinician knowledge on importance/implementation of nutrition and lifestyle changes Side Effects and Costs of GLP-1 Medications The use of GLP-1 drugs has been associated with numerous side effects, ranging from mild to severe

She explained that this loss of muscle can lead to a lower metabolic rate, sunken skin and even osteoporosis in severe cases

doi: 10.12688/f1000research.22092.1

Orphanet J