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3.1 Innate and adaptive immune response In rat models of systemic inflammation, a GLP-1 RA, exendin, significantly lowered pro-inflammatory cytokine levels, including IL-1, IL-6, TNF-, and interferon-gamma (IFN-) (41)

The 48-Hour Rule for Safe Semaglutide Timing Adjustments Medical guidelines suggest that taking semaglutide no more than 48 hours before or after your regularly scheduled injection day maintains therapeutic effectiveness while minimizing disruption

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Another consideration is timing
