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Key points included: Weight stigma influences how patients are assessed, diagnosed, and treated Patients in larger bodies may receive delayed or inappropriate care Fear of judgment can lead patients to avoid healthcare settings Weight stigma is not neutral, and it directly affects clinical outcomes
New potential indications for GLP-1 agonist should be also investigated, such as insulin resistance, prediabetes and sarcopenia
The glucagon receptor agonism component directly promotes hepatic lipid oxidation and reduces de novo lipogenesis, providing fat reduction that extends beyond what would be expected from weight loss alone
Interactions with other medications can affect how semaglutide and sertraline work
