does semaglutide make you grumpy 💉 Ozempic (Semaglutide): Benefits vs. Side Effects Ozempic is a GLP-1 (Glucagon-Like Peptide-1) receptor agonist. It mimics a hormone your body naturally produces to lower blood sugar after eat and slows The Psychological Side Effects of

Semaglutide is injected subcutaneously (under the skin)

This is particularly noteworthy because two competing oral small-molecule GLP-1 programs from Pfizer, lotiglipron (discontinued in 2023) and danuglipron (discontinued in April 2025), were terminated due to liver toxicity concerns

It has also been associated with renal failure and liver damage

In the long term, excessive sodium intake can lead to high blood pressure and increase the risk of heart disease, stroke, and obesity.Frequently Asked Questions About Wegovy and Diet For those starting Wegovy or considering giving the medication a try, it's normal to have questions, especially regarding diet and lifestyle changes that can impact the ability to meet weight loss and long-term health goals