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Any deviation suggests contamination or degradation
As a result of these findings, the collaborators suggested 'proglucagon 78-107 may be the incretin of the lower gut' (Holst, rskov, Vagn Nielsen, Schwartz)
When combined with insulin or sulfonylureas, dose adjustments of these medications are frequently necessary to reduce the risk of hypoglycemia, as the glucose-lowering effects may be additive
