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If you're interested in understanding how your genetics influence your response to semaglutide, the Precision Peptide Genetic Test ($99 add-on) maps 14 peptide pathways and 150+ genetic insights, including variants like GLP1R rs6923761 that affect GLP-1 receptor sensitivity
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It binds to GLP-1 receptors found on: Pancreatic -cells Stimulates glucose-dependent insulin secretion Pancreatic -cells Suppresses glucagon release during hyperglycemia Hypothalamic satiety centers Reduces appetite and food intake Gastrointestinal tract Delays gastric emptying, enhancing satiety This multi-site activity leads to improved glycemic control, reduced body weight, and cardiovascular benefits

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